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protein tyrosine phosphatase 1b inhibitory activity of anthraquinones and stilbenes

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  • protein tyrosine phosphatase 1b inhibitory activity of anthraquinones and stilbenes

    Hey there, I need to find any information about protein tyrosine phosphatase 1b inhibitory activity of anthraquinones and stilbenes, searched all the web couldn't find anywhere.

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  • #2
    Protein Tyrosine Phosphatase 1B inhibitory Activity of ... ; " Protein Tyrosine Phosphatase 1B inhibitory Activity of Anthraquinones and Stilbenes " Save as: AGRIS_AP RIS EndNote(XML) Lookup the document at: ... PTP1B inhibitory activity and molecular docking analysis ... ; Among the isolated compounds, stilbene derivatives (7–9) showed a strong inhibitory effect on protein tyrosine phosphatase 1B (PTP1B) with IC 50 values ranging from 4.25 to 6.78 μM, which was significantly higher than that of the positive control, ursolic acid (IC 50 = 11.34 μM). Protein tyrosine phosphatase 1B inhibitory activity of ... ; Request PDF on ResearchGate | Protein tyrosine phosphatase 1B inhibitory activity of anthraguinones and stilbenes | Protein tyrosine phosphatase IB (PTP1B) is emerging as a potential therapeutic ... Novel Anthraquinone-based Derivatives as Potent Inhibitors ... ; Action of the new synthesized compounds on tyrosine kinase activity was showed. The anthraquinones 1a-c, 2a-b, 3 and 4a, b, d cause inhibitory effect on the activity of membrane-associated tyrosine kinases (fig. 2) within of 60-82%. Inhibition effect in research concentration of thiazole 2c and amino acid derivative 4c is absent (obtained ... PTP1B inhibitory activity and molecular docking analysis ... ; Among the isolated compounds, stilbene derivatives (7–9) showed a strong inhibitory effect on protein tyrosine phosphatase 1B (PTP1B) with IC50 values ranging from 4.25 to 6.78 μM, which was ... Promising Inhibitory Effects of Anthraquinones ... ; The present work aims to evaluate the anti-diabetic potentials of 16 anthraquinones, two naphthopyrone glycosides, and one naphthalene glycoside from Cassia obtusifolia via inhibition against the protein tyrosine phosphatases 1B (PTP1B) and α-glucosidase. Among them, anthraquinones emodin and alaternin exhibited the highest inhibitory activities on PTP1B and α-glucosidase, respectively. Inhibition of DNA topoisomerases I and II ... - SpringerLink ; Three anthraquinones ( 1, 2 and 4), three stilbenes ( 5, 6 and 7) and 3,5-dihydroxybenzyl alcohol ( 3) were isolated from Reynoutria japonica. Their structures were identified as emodin ( 1),... Inhibition of DNA topoisomerases I and II of compounds from Reynoutria japonica | SpringerLink Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors from ... ; As part of our ongoing search for new antidiabetic agents from medicinal plants, we found that a methanol extract of Morinda citrifolia showed potential stimulatory effects on glucose uptake in 3T3-L1 adipocyte cells. Bioassay-guided fractionation of this active extract yielded two new lignans (1 and 2) and three new neolignans (9, 10, and 14), as well as 10 known compounds (3–8, 11–13 ... Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors from ... ; As part of our ongoing search for new antidiabetic agents from medicinal plants, we found that a methanol extract of Morinda citrifolia showed potential stimulatory effects on glucose uptake in 3T3-L1 adipocyte cells. Bioassay-guided fractionation of this active extract yielded two new lignans (1 and 2) and three new neolignans (9, 10, and 14), as well as 10 known compounds (3–8, 11–13 ...Novel Anthraquinone-based Derivatives as Potent Inhibitors ... ; Action of the new synthesized compounds on tyrosine kinase activity was showed. The anthraquinones 1a-c, 2a-b, 3 and 4a, b, d cause inhibitory effect on the activity of membrane-associated tyrosine kinases (fig. 2) within of 60-82%. Inhibition effect in research concentration of thiazole 2c and amino acid derivative 4c is absent (obtained ... Bioactive secondary metabolites produced by an endophytic ... ; 3/29/2017 · Fangkrathok, N., Sripanidkulchai, B., Umehara, K. & Noguchi, H. Bioactive ergostanoids and a new polyhydroxyoctane from Lentinus polychrous mycelia and their inhibitory … (PDF) Promising Inhibitory Effects of Anthraquinones ... ; The present work aims to evaluate the anti-diabetic potentials of 16 anthraquinones, two naphthopyrone glycosides, and one naphthalene glycoside from Cassia obtusifolia via inhibition against the protein tyrosine phosphatases 1B (PTP1B) and NAVER Academic > Protein tyrosine phosphatase … ; Protein tyrosine phosphatase 1B (PTP1B) is emerging as a potential therapeutic target for the treatment of type-2 diabetes and obesity. To search for new types of PTP1B inhibitors, we have undertaken in vitro enzyme assay for some anthraquinones and stilbenes isolated from plants. Chalcone derivatives from the root bark of Morus alba L ... ; Protein tyrosine phosphatase 1B (PTP1B, human recombinant) and dithiothreitol (DTT) were purchased from Biomol ® International LP (Plymouth Meeting, PA, USA) and Bio-Rad Laboratories (Hercules, CA, USA), respectively. All chemicals and solvents used in column chromatography and assays were of reagent grade and were purchased from commercial ... www.nature.com ; www.nature.com US9504725B2 - Compositions and functional foods for ... ; US9504725B2 US13/498,247 US200913498247A US9504725B2 US 9504725 B2 US9504725 B2 US 9504725B2 US 200913498247 A US200913498247 A US 200913498247A US 9504725 B2 US9504725 B2 US 9504725B2 Authority US United States Prior art keywords polygonum cuspidatum fraction fat obesity butanol Prior art date 2009-12-29 Legal status (The legal status is an assumption and is not a legal … osine PhosphatryProtein T ase 1B inhibitory Activity of ... ; PTP1B activity at high concentration of 30 µ g/mL. Our findings suggest that the hypoglycemic effect of anthraquinones may be associated with their PTP1B inhibitory activity. Keywords Protein tyrosine phosphatase 1B (PTP1B), anthraquinones, stilbenes, in vitro enzyme assay Introduction Insulin plays an important role in the regulation of Phuong Thien Thuong - Google Scholar Citations ; Their combined citations are counted only for the first article. Merged citations. This "Cited by" count includes citations to the following articles in Scholar. The ones marked * may be different from the article in the profile. Add co-authors Co-authors. Upload PDF. PDF Restore Delete Forever. Tran Hung - Academia.edu ; The inhibition kinetics analyzed by Lineweaver-Burk plots found that they were competitive inhibitors with the linoleic acid at the active site of lipoxygenase. In addition, stilbenes exhibited significantly free radical scavenging activity against ABTS(.+) with trolox equivalent activity …Novel Anthraquinone-based Derivatives as Potent Inhibitors for ... - NCBI ; Inhibitors of protein tyrosine kinase activity of the membrane fraction, as promising ... Keywords: Anthraquinone, thiourea, thiazole, triazole, amino acid, protein .... tyrosine phosphatase 1B inhibitory activity of anthraquinones and stilbenes. Protein tyrosine phosphatase 1B inhibitory activity of Indonesian ... ; 30 May 2012 ... Protein tyrosine phosphatase 1B inhibitory activity of Indonesian herbal medicines and constituents of Cinnamomum burmannii and Zingiber ... Promising Inhibitory Effects of Anthraquinones, Naphthopyrone ... - MDPI ; 27 Dec 2016 ... Protein tyrosine phosphatases 1B (PTP1B), a member of the PTP .... Inhibitory Activity of Anthraquinones, Naphthopyrone Glycosides, and a ... Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors from Morinda ... ; 13 Nov 2013 ... Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitors from Morinda citrifolia (Noni ) and Their Insulin Mimetic Activity ... Compounds 3, 6, 7, and 15 showed inhibitory effects on PTP1B enzyme with IC50 values of 21.86 ± 0.48, 15.01 ± 0.20, 16.82 ± 0.42, and .... Novel stilbenes from Artocarpus nanchuanensis. Anti-obesity and hypolipidemic effects of Rheum ... - Semantic Scholar ; phosphatase 1B inhibition. Woojung Lee1 ... Protein tyrosine phosphatase 1B ( PTP1B) is important in the regu- lation of ... showed PTP1B inhibitory activity of a hot water extract of RU. (12). ... anthraquinone derivatives (chrysophanol and physcion) through .... thranoids and stilbenes (9), its metabolic regulatory effects might. Stilbenes contribute to the anticancer effects of Rheum undulatum L ... ; 14 Jan 2019 ... Numerous stilbenes isolated from R. undulatum have been revealed ..... C57BL/6 mice through protein tyrosine phosphatase 1B inhibition. ... Yoshikawa M and Kubo M: Study on anti-Oketsu activity of rhubarb II. ... HJ and Lee KR: Antidiabetic stilbene and anthraquinone derivatives from Rheum undulatum. Natural Product Sciences | RG Journal Impact Rankings 2017 and 2018 ; Protein tyrosine phosphatase 1B inhibitory activity of anthraguinones and stilbenes ... enzyme assay for some anthraquinones and stilbenes isolated from plants. chrysophanic acid, 481-74-3 - The Good Scents Company ; PubMed:Antidyslipidemic effect and antioxidant activity of anthraquinone .... diet- fed C57BL/6 mice through protein tyrosine phosphatase 1B inhibition. ..... PubMed:Antidiabetic stilbene and anthraquinone derivatives from Rheum undulatum. Phuong Thien Thuong - Trích dẫn của Google Scholar ; Antioxidant activity of caffeoyl quinic acid derivatives from the roots of ... kaki ( persimmon) and their inhibitory effects on protein tyrosine phosphatase 1B ... Antioxidant Activity of Anthraquinones and Flavonoids from Flower ... Stilbenes and oligostilbenes from leaf and stem of Vitis amurensis and their cytotoxic activity. キャパシティ 押す
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  • #3
    You can win something on that site.

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  • #4
    Yes, but it's very rare.

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  • #5
    Thanks.

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  • #6
    Thanks guys, looked for this long time too.

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  • #7
    Oh man, that's great, thank, solid website, found what I needed.

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  • #8
    Topic is closed

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